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Home > Canvax Metabotropic Glutamate Receptor 4 G0560-B

Canvax Metabotropic Glutamate Receptor 4 G0560-B

Canvax Metabotropic Glutamate Receptor 4 G0560-B


Metabotropic Glutamate Receptor 4, ExpressMAX™ Human GPCR ORF Clones

Metabotropic Glutamate Receptor 4 is a member of the GPCR family and is encoded in Humans by the GRM4 gene. GRM4, GRM6, GMR7 and GRM8 belong to group III of the metabotropic glutamate receptor. L-glutamate is the major excitatory neurotransmitter in the Central Nervous System and activates both ionotropic and metabotropic glutamate receptors. These receptors inhibit of the cyclic AMP cascade. Activation of GRM4 has potential therapeutic benefits in the treatment of Parkinson´s disease. Taste GRM4 is involved in the perception of umami.

Main Features:

Native structure. Wide range: a large collection of ExpressMAX™ GPCR ORF Clones availables. Highest levels of GPCR expression: on surface cell lines, > 50% of TAG detection by cytometry. Wide spectrum: of strong constitutive promoters. Complete solution: it contains all necessary elements for maximum receptor expression. Ready-to-use solution: avoids cloning steps, DNA ready to transfect. Easy protocol and detection: the whole procedure is simple, with minimal handling. Neomycin resistance. Ampicillin bacterial selection.

Includes: Includes for 15 µg: ExpressMAX™ GPCR ORF Clones (Cat. No. -A & B) - 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL) Mammalian Transfection Kits (Cat. No. -PLUS): - 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL) - 0.2 mL CANFAST™ Transfection Reagent (15 µg = 15 assays)

Applications: Functional assays, as protein immobilization, cellular localization and other functional assays. High-throughput and large scale protein production and purification. Reverse transfection arrays and nucleic acid programmable protein arrays (NAPPA).

Format: 15 µL
Shipping conditions: Dry Ice
Storage Conditions: -20 ºC
Manufacturer P/nG0560 - B