Canvax Dopamine Receptor D2 G0546-A

Dopamine Receptor D2, ExpressMAX™ Human GPCR ORF Clones

Dopamine Receptor D2 is a member of the GPCR family and it is encoded in Humans by the DRD2 gene. Alternative splicing of this gene results in two different isoforms. There is a third form but it is not known whether it is actually a splicing aberration or a normal form. A missense mutation in this gene causes myoclonus dystonia and others mutations have been associated with schizophrenia. It inhibits adenylyl cyclase activity. Regulating the expression of this receptor in mice, controls synaptic plasticity, memory and exploration.

Main Features:

Native structure. Wide range: a large collection of ExpressMAX™ GPCR ORF Clones availables. Highest levels of GPCR expression: on surface cell lines, > 50% of TAG detection by cytometry. Wide spectrum: of strong constitutive promoters. Complete solution: it contains all necessary elements for maximum receptor expression. Ready-to-use solution: avoids cloning steps, DNA ready to transfect. Easy protocol and detection: the whole procedure is simple, with minimal handling. Neomycin resistance. Ampicillin bacterial selection.

Includes: Includes for 15 µg: ExpressMAX™ GPCR ORF Clones (Cat. No. -A & B) - 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL) Mammalian Transfection Kits (Cat. No. -PLUS): - 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL) - 0.2 mL CANFAST™ Transfection Reagent (15 µg = 15 assays)

Applications: Functional assays, as protein immobilization, cellular localization and other functional assays. High-throughput and large scale protein production and purification. Reverse transfection arrays and nucleic acid programmable protein arrays (NAPPA).