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Canvax Histamine Receptor H1 G0561-Plus
PART NO: CX-G0561-PLUS
Histamine Receptor H1, ExpressMAX™ Human GPCR ORF Clones
Histamine Receptor H1 is a member of the Rhodopsin like GPCR family. It is activated by the biogenic amine histamine. HRH1 is expressed in smooth muscles, in the heart and in the Central Nervous System. It is linked to an intracellular G-protein (Gq) that activates phospholipase C and the phosphatidylinositol signaling pathway. Antihistamines are used as anti-allergic Drugs. The production of prostaglandin E2 synthase induces the histamine release from neurons, causing systemic vasodilation, contraction of smooth muscles and increased capillary permeability due to its action on HRH1.
Main Features:
Native structure. Wide range: a large collection of ExpressMAX™ GPCR ORF Clones availables. Highest levels of GPCR expression: on surface cell lines, > 50% of TAG detection by cytometry. Wide spectrum: of strong constitutive promoters. Complete solution: it contains all necessary elements for maximum receptor expression. Ready-to-use solution: avoids cloning steps, DNA ready to transfect. Easy protocol and detection: the whole procedure is simple, with minimal handling. Neomycin resistance. Ampicillin bacterial selection.
Includes: Includes for 15 µg: ExpressMAX™ GPCR ORF Clones (Cat. No. -A & B) - 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL) Mammalian Transfection Kits (Cat. No. -PLUS): - 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL) - 0.2 mL CANFAST™ Transfection Reagent (15 µg = 15 assays)
Applications: Functional assays, as protein immobilization, cellular localization and other functional assays. High-throughput and large scale protein production and purification. Reverse transfection arrays and nucleic acid programmable protein arrays (NAPPA).
Histamine Receptor H1 is a member of the Rhodopsin like GPCR family. It is activated by the biogenic amine histamine. HRH1 is expressed in smooth muscles, in the heart and in the Central Nervous System. It is linked to an intracellular G-protein (Gq) that activates phospholipase C and the phosphatidylinositol signaling pathway. Antihistamines are used as anti-allergic Drugs. The production of prostaglandin E2 synthase induces the histamine release from neurons, causing systemic vasodilation, contraction of smooth muscles and increased capillary permeability due to its action on HRH1.
Main Features:
Native structure. Wide range: a large collection of ExpressMAX™ GPCR ORF Clones availables. Highest levels of GPCR expression: on surface cell lines, > 50% of TAG detection by cytometry. Wide spectrum: of strong constitutive promoters. Complete solution: it contains all necessary elements for maximum receptor expression. Ready-to-use solution: avoids cloning steps, DNA ready to transfect. Easy protocol and detection: the whole procedure is simple, with minimal handling. Neomycin resistance. Ampicillin bacterial selection.
Includes: Includes for 15 µg: ExpressMAX™ GPCR ORF Clones (Cat. No. -A & B) - 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL) Mammalian Transfection Kits (Cat. No. -PLUS): - 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL) - 0.2 mL CANFAST™ Transfection Reagent (15 µg = 15 assays)
Applications: Functional assays, as protein immobilization, cellular localization and other functional assays. High-throughput and large scale protein production and purification. Reverse transfection arrays and nucleic acid programmable protein arrays (NAPPA).
| Format: 15 µL + 0.2 mL Shipping conditions: Dry Ice Storage Conditions: -20 ºC | |
| Manufacturer | Canvax |
| Manufacturer P/n | G0561 - Plus |