Canvax Histamine Receptor H2 G0562-A

Histamine Receptor H2, ExpressMAX™ Human GPCR ORF Clones

Histamine Receptor H2 is a member of the Rhodopsin like GPCR family. HRH2 is positively coupled to adenylate cyclase via Gs and is a potent stimulant of cAMP production, increases the intracellular Ca2+ levels and releases Ca2+ from intracellular stores. It is in the gastric parietal cells, vascular smooth muscle, neutrophils, Central Nervous System, heart and uterus. HRH2 stimulates gastric acid secretion, regulates gastrointestinal motility and intestinal secretion, smooth muscle relaxation and inhibit antibody production, T-cell proliferation and cytokine synthesis.

Main Features:

Native structure. Wide range: a large collection of ExpressMAX™ GPCR ORF Clones availables. Highest levels of GPCR expression: on surface cell lines, > 50% of TAG detection by cytometry. Wide spectrum: of strong constitutive promoters. Complete solution: it contains all necessary elements for maximum receptor expression. Ready-to-use solution: avoids cloning steps, DNA ready to transfect. Easy protocol and detection: the whole procedure is simple, with minimal handling. Neomycin resistance. Ampicillin bacterial selection.

Includes: Includes for 15 µg: ExpressMAX™ GPCR ORF Clones (Cat. No. -A & B) - 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL) Mammalian Transfection Kits (Cat. No. -PLUS): - 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL) - 0.2 mL CANFAST™ Transfection Reagent (15 µg = 15 assays)

Applications: Functional assays, as protein immobilization, cellular localization and other functional assays. High-throughput and large scale protein production and purification. Reverse transfection arrays and nucleic acid programmable protein arrays (NAPPA).