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Home > Laboratory > Life Sciences > Molecular Cell Biology > GPCR ORF Clones > Canvax Endothelin Receptor type B G0548-A

Canvax Endothelin Receptor type B G0548-A

Canvax Endothelin Receptor type B G0548-A


Endothelin Receptor type B, ExpressMAX™ Human GPCR ORF Clones

Endothelin Receptor type B is a member of the GPCR family, encoded in Humans by the EDNRB gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene and it exhibit different responses upon binding. Mutations in this gene cause Hirschsprung disease type 2 and in melanocytic cells, the mutated EDNRB gene is linked to Waadenburg syndrome. It activates a phosphatidylinositol-calcium second messenger system.

Main Features:

Native structure. Wide range: a large collection of ExpressMAX™ GPCR ORF Clones availables. Highest levels of GPCR expression: on surface cell lines, > 50% of TAG detection by cytometry. Wide spectrum: of strong constitutive promoters. Complete solution: it contains all necessary elements for maximum receptor expression. Ready-to-use solution: avoids cloning steps, DNA ready to transfect. Easy protocol and detection: the whole procedure is simple, with minimal handling. Neomycin resistance. Ampicillin bacterial selection.

Includes: Includes for 15 µg: ExpressMAX™ GPCR ORF Clones (Cat. No. -A & B) - 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL) Mammalian Transfection Kits (Cat. No. -PLUS): - 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL) - 0.2 mL CANFAST™ Transfection Reagent (15 µg = 15 assays)

Applications: Functional assays, as protein immobilization, cellular localization and other functional assays. High-throughput and large scale protein production and purification. Reverse transfection arrays and nucleic acid programmable protein arrays (NAPPA).

Format: 15 µL
Shipping conditions: Dry Ice
Storage Conditions: -20 ºC
Manufacturer P/nG0548 - A