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Home > Canvax Chemokine (C-X-C motif) Receptor 3 (isoform 2) G0636-B

Canvax Chemokine (C-X-C motif) Receptor 3 (isoform 2) G0636-B

Canvax Chemokine (C-X-C motif) Receptor 3 (isoform 2) G0636-B


Chemokine (C-X-C motif) Receptor 3 (isoform 2), ExpressMAX™ Human GPCR ORF Clones

It is a GPCR with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-?), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for the gene. This isoform (isoform 2) has a longer and distinct N-terminus compared to isoform 1. This isoform acts as functional receptor for chemokine CXCL4/PF4.

Main Features:

Native structure. Wide range: A large collection of ExpressMAX™ GPCR ORF Clones availables. Highest levels of GPCR expression: on surface cell lines, > 50% of TAG detection by cytometry. Wide spectrum: of strong constitutive promoters. Complete solution: it contains all necessary elements for maximum receptor expression. Ready-to-use solution: avoids cloning steps, DNA ready to transfect. Easy protocol and detection: the whole procedure is simple, with minimal handling. Neomycin resistance. Ampicillin bacterial selection.

Includes: Includes for 15 µg: ExpressMAX™ GPCR ORF Clones (Cat. No. -A & B) - 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL) Mammalian Transfection Kits (Cat. No. -PLUS): - 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL) - 0.2 mL CANFAST™ Transfection Reagent (15 µg = 15 assays)

Applications: Functional assays, as protein immobilization, cellular localization and other functional assays. High-throughput and large scale protein production and purification. Reverse transfection arrays and nucleic acid programmable protein arrays (NAPPA).

Format: 15 µL
Shipping conditions: Dry Ice
Storage Conditions: -20 ºC
Manufacturer P/nG0636 - B